Should be taken with food: Take immediately after meals.
Contraindications
Hypersensitivity. Stroke (CVA), heart attack (MI), CABG, uncontrolled HTN, CHF (NYHA II-IV). Patients in whom aspirin or other NSAIDs induce symptoms of bronchospasm, allergic rhinitis or urticaria. Active ulceration or chronic inflammation of either the upper or lower GIT. Treatment of peri-op pain in the setting of CABG. Severe renal & hepatic failure; heart failure.
May interfere w/ aspirin's prophylactic treatment of CV disease. May enhance response to oral anticoagulants. Reduce efficacy of diuretics & other antihypertensives including ACE inhibitors, AIIA & β-blockers. Increased risk of GI ulceration or bleeding w/ corticosteroids; nephrotoxicity w/ cyclosporine & tacrolimus. Insulin or oral hypoglycemics. Increased plasma levels of lithium & methotrexate.
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